Joint analysis of longitudinal and recurrent event data: A functional regression approach with autoregressive frailty

Published in
In Statistical Methods in Medical Research, 35(7), 1463–1479, 2026.
Publication type
Journal article

Abstract

This paper combines functional principal component analysis with autoregressive frailty models to jointly analyze sparse longitudinal measurements and recurrent events. The approach accommodates changing relationships over time and is evaluated through simulations and applications to blood-pressure and kidney-stone studies.